Obesity Abstracts

Obesity is not simply a behavioural or lifestyle issue, but a set of complex chronic and relapsing diseases worthy of the same consideration as any other life-threatening diseases. While obesity is often viewed as a single risk factor for other diseases, there are in fact many distinguishable subpopulations living with different types of obesity, including those defined by risks of complications and others by optimal treatment response. While subpopulations will overlap, the d...

Background: Approximately 15-25% of the world population has non-alcoholic fatty liver disease (NAFLD) and nearly quarter go on to develop non-alcoholic steatohepatitis (NASH). Obesity and T2DM are strong risk factors with prevalence of NAFLD rising to 90% in obesity and 60% in T2DM. Liver biopsy remains the gold standard in diagnosis and prognosis; nevertheless, it is expensive and invasive. The underlying fibrosis stage is key in determining clinical outcome...

Liraglutide 3 mg daily is an approved, prescription injectable GLP-1 receptor agonist, which can reduce weight in patients with obesity, with or without obesity complications. We conducted a 24-week, open-label real-world study involving 62 participants with a BMI >30 kg/m2 or >27 kg/m2 if they had co-existing dyslipidaemia or hypertension. No patients had type 2 diabetes. Patients received once-daily subcutaneous liraglutide 3.0 mg, alongside NHS...